The Pre is widely seen as a rival to other popular smartphones
The Palm Pre will go on sale on 6 June in the US and will only be available on the Sprint network.
The much-anticipated handset will cost $199.99 (£129), after a rebate, and buyers must take out a two-year contract when signing up.
Palm said it expected the phone to be available nationwide at launch and has signed up four stores to put the gadget on their shelves.
No date has been given for when the handset will launch in the UK.
First announced at the Consumer Electronics Show in Las Vegas in January 2009, the Pre has generated a huge amount of interest largely thanks to Palm's long history in personal data devices.
The Pre impressed many with its operating system, which is geared towards working with the websites, such as social networks and e-mail services, people use when out and about.
The phone automatically recognises when owners connect to social or e-mail services and builds up a global list of contacts and login details as it is used.
Unlike many other phones, the handset also allows owners to have several different applications running at the same time.
The phone also has an innovative interface based around its touch screen and a "gesture area" below the display.
The phone will use Sprint's 3G network and buyers are recommended to take out an unlimited data plan as the phone swaps a lot of information back and forth as it is being used.
The phone is widely seen as a rival to other smartphones such as Apple's iPhone, Android handsets and RIM's Blackberry.
Also on sale at launch will be the wireless charging system. This will not be included in the basic bundle for the phone but will cost an additional $69.99 (£45) for the Touchstone dock and cover for the Pre.