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Thursday, 21 May, 1998, 13:54 GMT 14:54 UK
Is winning in your genes?
![]() Some us may just be born to win
An athlete's ability to excel could be down to his or her genes, according to new research by British scientists.
Researchers at the Centre for Cardiovascular Genetics at University College London have managed to isolate a gene they think is responsible for enhancing physical endurance and sporting performance. The gene influences the production of an enzyme which increases blood pressure and it also appears to boost the intake of oxygen and nutrients to muscle cells. Hope for heart patients It is hoped that the gene - which has been named ACE, short for a polymorphism of the angiotensin converting enzyme - could also help to improve the treatment of stroke and heart patients.
"During heart attacks and strokes, where blood supply is blocked, a means of increasing efficiency in neighbouring cells will be a crucial advance in treatment." There are two different types of the ACE gene, named I and D. Because of the way genes are paired, humans can fall into three categories II, DD or ID.
Genetic samples were also taken from a group of high-altitude mountaineers who regularly climbed without breathing equipment. Scientists found that most of them had ID or II gene combinations. None of the mountaineers who could climb above 8000m without oxygen had the DD version. Dr Montgomery, who published the results in the science journal Nature, said: "We have demonstrated that version I alleles are associated with better endurance performance than the D allele." But he said more studies will be needed to discover if the results are the same in women and other racial groups. |
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