Guinea Pig Kids was broadcast in the UK on Tuesday, 30 November, 2004 at 1930 GMT on BBC Two.
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The comments published on this page reflect the balance of views we received.
Like many others, this is the first time I've written into a programme. I haven't been able to stop thinking about these children all day. Is there anything more we can do? Please repeat this programme and publicise it more prominently. More people need to be made aware of this issue.
Words cannot describe how I felt after watching this programme. If there is anything we can do to help highlight this situation please let us know.
Millie Neil, Manchester
This was one of the most heartbreaking and disturbing documentaries I have ever seen - especially in New York City where I'm from. What are these children's rights in a democracy? What can be done?
I've never written in like this before, but I was left in shock by these revalations. For the first time, I feel not only moved or saddened or cynical, but compelled to do something. Anything.
Ben Williams, London
Complete utter and appalling rubbish. It never once addressed the issue of how children are supposed to access the latest, more effective, more tolerable treatment for HIV. The programme was fundamentally flawed and used every opportunity to talk about toxicity instead of the lifes saved through newer treatment.
Simon Collins, London
If it wasn't for the BBC, people in America would never know about things like this.
Byron, San Antonio
This is just unbelivable! I can't believe this is really happening. In New York?! How is this posible?
Thanks for such an informative yet heart-wrenching programme. I immediately e-mailed the ACS in America.
Sandra Davis, Hertfordshire
I was so upset by this programme and hope that something can be done to persuade the authorities in New York that the trials must be stopped.
I have never before written into a programme but was so horrified by this documentary that I felt compelled to write. I would even like to find out what else can be done to highlight this further.
Buckley Rosemarie, Burnley
We all want a vaccine or a non-toxic drug to be developed to save or improve the lives of people with HIV but at this cost? No way!!!
Dawn McGrath, East Sussex
Did I just see what I think I saw? Can someone pinch me please, as prior to watching this programme I thought I was living in the 21st Century. Horrific, unbelievable, inexcusable.
Lindsay Hodgson, Gateshead
One of the saddest programmes I have ever watched. Thank you for showing it.
Catherine Njuguna, London
Thank you so much for bringing this to our notice in this country. Hopefully it will make some difference to defenceless children.
Susan Shaw-Cooper, UK
I think this is absolutely horrendous. It should be stopped immediately.
All parties involved in this scandal must be exposed and these experiments must be stopped.
David Robertson, London
We are two HIV positive people who have undergone the medication these poor children are being subjected to and we understand the terrible side-effects suffered. We had the choice of whether we wanted to continue some of our pill regimes and often stopped them because of the awful side-effects. What can we do to free these poor children and give them the rights they are due?
Martin & Stephen, Brighton & Hove
I am 11 years old and just watched your programme. My cousins live in New York City and it frightens me that this kind of thing goes on. I fear for the children, especially the ones who cannot speak up.
Katie Wilson, Ipswich
As a parent I found this almost unwatchable.
Iain Biggs, Bristol
I caught this programme halfway through but I was so affected by it. How can this be allowed to go on? It is shameful and those responsible should be brought to justice. I'm just so appalled, especially by the case of the two half-sisters who were doing so well off the drugs and then were taken away from their adoptive family. I can't describe how sorry I feel for them.
Uzo Mkparu, London
I feel completely disgusted. How can this kind of practice be going on? Red tape and bureaucracy have no place when dealing with children's lives.
Peter Watkin, Bristol
I had to fight my tears watching the terrible situation these children are in. How is this possible in this day and age?
Elle Maessen, The Netherlands
I'm in shock after this programme and for the first time in a long time find myself in tears of pity, rage and frustration. Is there nothing that your average member of the public out here can do? Please, please tell us more!
Catherine Czerkawska, Ayrshire
Are there no international human rights laws that apply here? Thank you for this innovative investigative journalism - appalling to watch, but very well handled.
The documentary was excellent and has left me wanting to act on this. Is there anything we can do for these children?
Elizabeth Lancaster, Doncaster
Val Jones, Portishead
I was shocked to the core by this programme. Words can not express the sympathy that I feel for the parents and children involved. How can this possibly be allowed to continue in the "free" world? What can we do to help?
Congratulations to the BBC for not only having the guts to investigate but actually broadcast a piece so inflammatory. It will be interesting to see if you have the courage of your convictions and investigate further.
Chris Mackinnon, Edinburgh
Disgusting and unforgivable to use these children, whose lives have already been dealt a huge blow.
Mark Neve, Stubbington
This is news to me. I wish that the news here in the USA would pick this story up. I really thought that those days were over.