Question Time, the BBC's premier political programme, will be in Cardiff on 17 March.
David Dimbleby will be joined for the interactive debate by Rhodri Morgan, Julie Kirkbride MP, Simon Thomas MP, broadcaster and comedian Sandi Toksvig and director-general of the CBI Sir Digby Jones.
Title: First Minister of the Welsh Assembly
Career: Rhodri Morgan has been First Minister and Labour Party leader in Wales since 2000.
He was first elected MP for Cardiff West in 1987 and served as Labour's front bench spokesperson on Energy and on Welsh Affairs.
A graduate of Oxford and Harvard Universities, he worked as a civil servant for the DTI before heading the European Commission Office in Wales.
JULIE KIRKBRIDE MP
Title: Conservative MP for Bromsgrove
Career: Julie Kirkbride was shadow secretary of state for Culture, Media and Sport until a reshuffle last September.
She has campaigned for the right of parents to choose single vaccinations rather than the MMR jab and has defended the Sun's Page 3 girls.
Prior to her election in 1997, Ms Kirkbride was a political correspondent with the Daily Telegraph and later social affairs editor on the Sunday Telegraph.
Title: Broadcaster, comedian and writer
Career: Sandi Toksvig is a regular panellist on Call My Bluff and Whose Line is it Anyway?
She is a prominent Liberal Democrat supporter and was backed by the party in an unsuccessful bid to become Chancellor of Oxford University by campaigning against student fees.
Born in Denmark, she studied law and anthropology at Cambridge University. She currently hosts a daily programme on London's LBC radio.
SIMON THOMAS MP
Title: Plaid Cymru Director of Policy
Career: Simon Thomas was the first MP elected in the new millennium at the Ceredigion by-election.
He has called for Tony Blair to publish legal advice on the Iraq war and is demanding an investigation into whether Tony Blair broke ministerial rules.
He initially attracted attention for being the first male MP in living memory to wear an earring in the Commons but has since become known for his high profile parliamentary presence.
SIR DIGBY JONES
Title: Director-General of the CBI
Career: Sir Digby has led the CBI since 2000, travelling the world to promote UK business.
After a spell in the Royal Navy, Digby Jones worked in corporate law, before joining consultants KPMG in 1998.
He was appointed a Knight Bachelor in the 2005 New Year Honours List. He includes rugby and military history among his interests.
BBC ONE's Question Time is broadcast on Thursdays at 2235 GMT.