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Wednesday's programme, presented by Jeremy Paxman, covers the following stories:
The Europe Minister Douglas Alexander has confirmed that "it doesn't matter what other countries do, we'll have a vote on the constitution".
But with polls showing the public are opposed to the new treaty by a large margin, Stephanie Flanders is investigating whether the Yes campaign has a chance of winning over the public.
Tim Whewell is in the Uzbek border town of Korasuv.
He has an interview with one rebel leader who has announced an Islamic uprising in his town.
A force for change
Newsnight has spent a week with the controversial Chief Constable of North Wales.
Richard Watson explains how Richard Brunstrom is raising more money for frontline policing by turning the force into a business.
And we can reveal definitive proof that voting in the Eurovision song contest is not as it seems.
New research from Oxford University shows what we all suspected - it's not the quality of the song that matters but where the singer hails from.
Newsnight turned 25 on 30 January 2005. You can visit our special anniversary website to find out more about the programme's history and watch the first Newsnight ever broadcast.