Apollo 8 was the first manned mission to orbit the Moon, and the first to witness the spectacular sight of Earth rising over the lunar surface.
Spectators watch from the press site at Kennedy Space Center, Florida, as Apollo 11 launches atop the massive Saturn V rocket on 16 July 1969.
This grainy, black and white screenshot from a TV camera mounted on the Apollo 11 lander captures the moment Neil Armstrong became the first human to set foot on the Moon.
Apollo 11's Edwin "Buzz" Aldrin poses for a picture in the Moon's Sea of Tranquility. The mission's commander Neil Armstrong took the picture with a 70mm camera.
After lifting off from the Moon's surface, the Apollo 11 lunar module approaches its orbiting "mothership", ahead of the return journey to Earth.
After splashing down in the Pacific, the Apollo 11 astronauts were placed in a mobile quarantine facility - a precaution against "lunar bugs". The Moon turned out to be devoid of life.
The Apollo 11 astronauts were welcomed home after their successful mission in a ticker tape parade described as the biggest in New York's history.
The words "Houston, we've had a problem" alerted Nasa to the explosion that crippled Apollo 13 in space. The astronauts made it safely back to Earth in April 1970.
Eugene A Cernan, commander of the Apollo 17 mission, took the Lunar Roving Vehicle for a ride across the Moon's Taurus-Littrow region in 1972.
Geologist-turned-astronaut Harrison Schmitt is dwarfed by a huge boulder called Tracy's Rock during the third moonwalk of the Apollo 17 mission.