1 of 8 The first major exhibition of works by the great Renaissance painter Raphael in the UK opens at the National Gallery, London, on Wednesday. This is a cartoon for the Mackintosh Madonna, dating from about 1509-11.
2 of 8 The Madonna of the Pinks, which was saved from export when the National Gallery raised £22m, is the centre of the exhibition.
3 of 8 Raphael started as a competent master of provincial church decoration and became one of the greatest painters who ever lived. The Garvagh Madonna, above, was painted in about 1509-10.
4 of 8 He was born in Urbino in 1483 and received his first instruction in the techniques of painting from his father, Giovanni Santi, a minor artist. Saint Sebastian, above, is from 1502-3.
5 of 8 Raphael spent four years in Perugia, learning from master Perugino before leaving his workshop in 1504. This painting shows The Holy Family with the Lamb, about 1507.
6 of 8 In his early works, Raphael remained faithful to the Perugino School. This image shows Saint Michael, painted about 1503-4.
7 of 8 In 1504, Raphael went to Florence and was influenced by a great debate about the future of art at the time. An Allegory (Vision of a Knight) was painted about 1504.
8 of 8 Raphael was influenced by Michelangelo and Leonardo as this image, Leda and the Swan (after Leonardo), about 1515, shows. Raphael died just five years later.