Page last updated at 01:44 GMT, Monday, 22 February 2010

Peanut allergies tackled in largest ever trial

Peanuts
The pilot study was the first time a food allergy had been desensitized

Doctors in Cambridge believe they may soon have a cure for peanut allergies.

The largest ever trial to find a treatment for potentially fatal peanut allergies is to give sufferers tiny amounts daily to build up tolerance.

The Addenbrookes team will give increasing doses of peanut flour to 104 British children, up to the equivalent of five nuts a day.

Twenty out of 23 sufferers in an earlier study became able to eat more than 30 peanuts safely.

The new £1m three-year trial could lead to a widely available treatment.

About one in 50 young people in the UK suffers from peanut allergies which can cause breathing problems, itching and, in severe cases, a potentially fatal inflammatory reaction called anaphylaxis.

The new trial funded by the Department of Health's Institute of Health Research will involve more than 100 seven to 17-year-olds.

They will be given daily doses of peanut flour, starting at about one milligram, added to yoghurt.

"This is going to be the largest trial of its kind in the world and it should give us a definitive idea of whether the approach works and whether it's safe," said Dr Andrew Clark.

The pilot study built up sufferers' tolerance to five nuts, or 800 milligrams, which was then taken as a maintenance treatment for at least six weeks.

A year on from the start of the study, 20 of the patients could eat 32 peanuts safely - meaning they no longer needed to screen food labels and be wary of what they ate.

The researchers believe a treatment could be available within two to three years.

But they warned against people attempting their own trials at home.



Print Sponsor


SEE ALSO
Better NHS anaphylaxis care call
08 Apr 09 |  Health
Hope over peanut allergy 'cure'
20 Feb 09 |  Health
Warning of nut allergy 'hysteria'
10 Dec 08 |  Health
Food allergy danger 'overstated'
31 Aug 06 |  Health

RELATED INTERNET LINKS
The BBC is not responsible for the content of external internet sites


FEATURES, VIEWS, ANALYSIS
Has China's housing bubble burst?
How the world's oldest clove tree defied an empire
Why Royal Ballet principal Sergei Polunin quit

BBC navigation

BBC © 2013 The BBC is not responsible for the content of external sites. Read more.

This page is best viewed in an up-to-date web browser with style sheets (CSS) enabled. While you will be able to view the content of this page in your current browser, you will not be able to get the full visual experience. Please consider upgrading your browser software or enabling style sheets (CSS) if you are able to do so.

Americas Africa Europe Middle East South Asia Asia Pacific