Europe South Asia Asia Pacific Americas Middle East Africa BBC Homepage World Service Education
BBC Homepagelow graphics version | feedback | help
BBC News Online
 You are in: Health
Front Page 
World 
UK 
UK Politics 
Business 
Sci/Tech 
Health 
Medical notes 
Background Briefings 
Education 
Sport 
Entertainment 
Talking Point 
In Depth 
AudioVideo 
Wednesday, 19 January, 2000, 19:20 GMT
CJD 'will not be an epidemic'

Brain CJD causes sponginess in the brain


The human form of mad cow disease (BSE) may eventually kill thousands of people, but is unlikely to become an epidemic, researchers have said.

Professor Liam Donaldson, chief medical officer for England, has admitted that nobody knows how many people will fall victim to variant Creutzfeldt-Jakob disease (vCJD).


1999 may be a bit of a turning point
Christl Donnelly, Wellcome Trust Centre for the Epidemiology of Infectious Disease
He has also refused to rule out the possibility that hundreds of thousands of people could be infected with the disease after eating beef products infected with BSE.

However, New Scientist magazine reports that the latest figures suggest that the final death toll is likely to be on the scale of thousands rather than millions.

Researchers at the Wellcome Trust Centre for the Epidemiology of Infectious Disease in Oxford have worked with statistics on how many infected cows were slaughtered, how much infected material entered the food chain and the course of the cattle epidemic.

From this, they have produced a model describing the likely course of Britain's vCJD epidemic.

Using figures on the number of cases in 1999 and 2000, they have predicted the maximum size of the epidemic.

Death rate vital


Cows CJD has been linked to BSE
If 15 people or fewer died from vCJD in 1999, the model predicts that any epidemic will reach a maximum of half a million cases in total.

If there is no increase and a similar number die in 2000, then it predicts that any epidemic will peak at a total of 14,000 cases or fewer.

So far, nine deaths from vCJD have been confirmed for 1999, according to the national CJD Surveillance Unit in Edinburgh.

It is still too early to put a final figure on the year's toll, but the current figure is less than that reported for 1998 at this stage last year. In January 1999, 12 deaths had been confirmed for 1998, a figure that eventually rose to 17.

Christl Donnelly, a statistician on the team, said: "It's good news that we haven't seen so many cases so far.

"1999 may be a bit of a turning point."

The model assumes that only a certain proportion of the population is susceptible to vCJD.


We are encouraged by the fact that CJD is not yet an epidemic, but we do not know how many people it is going to effect
Deartment of Health
All the known vCJD victims had two copies of a particular variant of the gene for a protein called PrP.

This trait is shared by about 40% of the British population.

However, it could be that other people are also susceptible, but will take longer to display symptoms.

A Department of Health spokesman said: "We are encouraged by the fact that vCJD is not yet an epidemic, but we do not know how many people it is going to effect, and we would be cautious about predicting a final figure."

Search BBC News Online

Advanced search options
Launch console
BBC RADIO NEWS
BBC ONE TV NEWS
WORLD NEWS SUMMARY
PROGRAMMES GUIDE

See also:
21 May 99 |  Health
CJD deaths could be on the rise
14 Jan 00 |  Health
CJD treatment 'draws closer'
21 Dec 99 |  Health
CJD: What is the risk?
18 Mar 99 |  Health
CJD families to sue government
01 May 99 |  Health
CJD mimics psychiatric disorders
26 Feb 99 |  Health
CJD warning over surgery
08 Jan 99 |  Health
CJD discovery in mice
13 Nov 99 |  Health
Blood test for CJD created

Internet links:

The BBC is not responsible for the content of external internet sites
Links to other Health stories are at the foot of the page.


E-mail this story to a friend

Links to more Health stories