Tests on some of the poultry found dead in Ukraine have shown that they had the lethal H5N1 bird flu strain.
Thousands of domestic birds have been culled in affected areas
The health ministry confirmed that the deadly strain of the virus was found in the Crimea peninsula.
Tests show it is present in 11 out of 25 villages which have been affected by the disease, a statement said.
The Ukraine president introduced a state of emergency in the affected region two weeks ago. There have been no human cases.
Neighbouring Russia and Romania have already reported outbreaks of the H5N1 strain of bird flu.
Ukraine officials have carried out tests on people in the Crimea and given vaccinations. Quarantines have also been imposed on some villages.
A mass cull of more than 50,000 domestic poultry has also been carried out.
The H5N1 strain of bird flu has killed nearly 70 people in Asia.