Take That are in the middle of their 20-date stadium tour
Pop survivors Take That have won their second coveted Silver Clef award, recognising an 18-year chart career.
The former boyband first received the prize in 1995, mere months before Robbie Williams quit.
On that occasion, so many fans packed the entrance to the Intercontinental Hotel in London that the group had to be ushered in through a side entrance.
They have now eclipsed the likes of Sir Paul McCartney and The Rolling Stones, who have only received the prize once.
The trophy is awarded each year to raise funds for music therapy charity Nordoff-Robins.
Brian Wilson was named best international act
Gary Barlow announced that he and his bandmates would donate £50,000 to the cause.
The group, who were en route to Wembley Stadium, were given their award by Lulu, who previously duetted with them on Relight My Fire.
Initially, Claire Sweeney had taken to the stage to present the trophy - but had to sit down again when Lulu arrived.
Laughing off the mix-up, Barlow said: "They messed that up, didn't they?"
Other winners at this year's ceremony at the London Hilton included Madness, who picked up the Icon award, and Queen, who were named Ambassadors of Rock.
Beach Boys' frontman Brian Wilson attended the ceremony to collect a trophy for Best International Act.
Picking up his accolade, the singer-songwriter shouted excitedly: "We all know music is a very, very, very big force in life."
On the opposite side of the musical spectrum, dance act N-Dubz were given the Digital Award, recognising their success with downloads, ringtones and streaming video.
Welsh rockers Stereophonics were named British Band of 2009, and La Roux were awarded Best Newcomer in the week they scored their first UK number one, with Bulletproof.
SILVER CLEF AWARDS 2009
Silver Clef Award - Take That
Icon Award - Madness
Classical Award - Faryl Smith
Ambassadors of Rock - Queen
Best British Band - Stereophonics
Digital Award - N-Dubz
International Award - Brian Wilson
Newcomer Award - La Roux (pictured)
The annual event, which has so far raised over £7.5m for Nordoff-Robbins, also featured an auction of one-off music memorabilia items, including a one-off Mini Cooper, designed by former Silver Clef recipient Paul Weller.
A £10 note signed by Take That was sold for £2,000.
Host Denise Van Outen later announced this year's event had raised more than £400,000 for the charity.
Take That, who scored their first hit in 1991, are in the middle of the biggest tour the UK has ever seen - playing to more than a million people at 20 stadium concerts.
They scored their first hit, Promises, in 1991, and went on to score eight number ones before splitting up in 1996.
Following a TV documentary in 2005, they reformed - without Williams - for a tour, which has led to two successful albums as a more mature form of boy band.
Their second Silver Clef will be a welcome addition to the trophy cabinet - as Williams claimed to have held on to the original one.
"We are honoured to win this, as we are with every award," he said after picking up the prize from TV presenter Gaby Roslin in 1995.
"We have a pitched battle in the band over who gets to take the award home. We start at each end of the pitch, then move into the middle to kick it out amongst ourselves.
"But I always win because I am a big lad and I was brought up on oatcakes - which is a good Staffordshire delicacy."