Lady Gaga performed at Glastonbury on Friday
US pop star Lady Gaga is to miss performing at a second Take That concert in Manchester due to illness.
Angry fans complained after the star failed to appear as one of the support acts at the Old Trafford Cricket Ground on Saturday, with no explanation given.
A spokesman for Lady Gaga told the BBC the star pulled out at the last-minute as she was "feeling unwell" and would not be performing on Sunday either.
He added she was "currently resting on doctor's orders".
"Lady Gaga was feeling unwell on Saturday and, after consulting her doctor, the decision was reluctantly taken that she was unable to perform with Take That at Old Trafford last night and tonight.
"Lady Gaga is currently resting on doctor's orders, but is looking forward to rejoining Take That at Wembley next weekend.
"She would like to thank Take That for supporting her decision, and apologise to the band and her fans for being unable to perform," he added.
Take That will finish their tour at Wembley on 5 July
The 50,000-strong crowd booed after a big screen notice announced on Saturday the singer would not be performing.
According to fans, first support act Gary Go entertained the audience instead, but began an hour later than originally scheduled.
A 31-year-old fan from Stockport said: "It was a bit disappointing because there was nothing to get you going. You were stood there like a sardine."
Margaret Graves, 58, of Hoylake, Wirral, said: "Gary Barlow said 'thanks to Gary Go who's got us out of a real spot'."
She added that Barlow apologised to fans for Lady Gaga's non-appearance and said: "'Don't get me started, you should have heard me backstage'."
Fans have been posting their disappointment on Take That's website with one writing: "How dare Lady Gaga not turn up? She lost herself 50,000 fans last night!"
The star performed a one-hour set at Glastonbury on Friday night.