Slumdog Millionaire stars Dev Patel and Freida Pinto
Danny Boyle's rags-to-riches tale Slumdog Millionaire has won the top film prize from Hollywood's producers.
It beat fellow nominees Milk, The Dark Knight, The Curious Case of Benjamin Button and Frost/Nixon at the Producers Guild of America (PGA) ceremony.
The award helps put the film in pole position for Oscar success, having received 10 nods including best film.
Earlier this month, the movie won four Golden Globes including best film and best director for Boyle.
The PGA award is considered an indicator for Oscar success as its members make up a large portion of the Academy of Motion Picture Arts and Sciences, which votes on the Oscars.
Last year's PGA best picture winner, No Country for Old Men, went on to win the top prize at the Academy Awards.
Other winners at the Los Angeles ceremony included Pixar film Wall-E, which won best animated film.
Best documentary went to Man on Wire, about a Frenchman who wire-walked between the Twin Towers in New York in 1974.
In the television categories, historical drama John Adams took the award for long-form TV and Mad Men picked up the drama prize.
Two shows were repeat winners from last year - 30 Rock was named best comedy while The Colbert Report won the prize for live entertainment.
Mariah Carey turns her hand to acting in Push
Slumdog Millionaire will compete against Brad Pitt's The Curious Case of Benjamin Button, Sean Penn's Milk, Michael Sheen's Frost/Nixon and Kate Winslet's The Reader for the top Oscar on 22 February.
Meanwhile, 1980s Harlem drama Push took the top prize at the Sundance Film Festival in Utah.
The film, based on the 1996 novel by the poet Sapphire and featuring singer Mariah Carey, won both the US cinema grand jury and audience awards at the showcase for independent film.
British film An Education, starring Emma Thompson, won the world cinema audience award.
The movie, adapted by writer Nick Hornby from an autobiographical essay by journalist Lynn Barber, tells of how she was seduced by an older man in 1960s London.
British documentary Afghan Star, chronicling the emergence of pop culture in Afghanistan, also picked up the directing and audience awards in the world cinema documentary categories.