Noah Wyle is reuturning to ER for its final season
A three-hour Heroes episode and the last ever ER series have been announced as part of NBC's new TV show line-up.
The US network has also commissioned a remake of 80s drama Knight Rider and a spin-off series to The Office, which will debut in February 2009.
Actresses Molly Shannon and Selma Blair feature in the US version of Australian comedy Kath & Kim and new drama My Own Worst Enemy will star Christian Slater.
Golden Globe winner Ian McShane has signed up to star in new drama Kings.
ER favourite Noah Wyle will return as Dr John Carter in the 15th and final season.
New series of Law & Order, Deal or No Deal and My Name is Earl have also been agreed.
The Office is due to be screened in the lucrative slot after the Super Bowl, which regularly picks up strong viewing figures in the wake of the annual sporting fixture.
Original content on NBC has nearly doubled compared to 10 years ago, the broadcaster said.