Director Joe Johnston is to take over the helm of horror remake The Wolf Man, about a man who becomes a werewolf, the film's producers are set to confirm.
Johnston also directed Honey, I Shrunk The Kids in 1989
Original director Mark Romanek left the film last month - just weeks before filming was due to start.
A spokesman for Universal said Johnston, 57, who directed 2004's Hidalgo, will be confirmed as replacement director this week.
The film stars Benicio del Toro, Sir Anthony Hopkins and Emily Blunt.
She previously appeared in The Devil Wears Prada, while Del Toro starred in Traffic and The Usual Suspects.
Production is expected to begin at Pinewood Studios, Buckinghamshire, next month after Romanek's departure put filming on hold.
Industry paper Hollywood Reporter said his departure from the film was due to a row over its budget.
If the current writer's strike continues, Johnston will not be able to alter the screenplay - written by Se7en scribe Andrew Kevin Walker - because of the Hollywood writers' strike.
As well as Hidalgo - starring Viggo Mortensen - Johnston also directed Jurassic Park III, Jumanji, The Rocketeer and 1989's Honey, I Shrunk The Kids.