Leonardo DiCaprio's roles as a mercenary and a policeman have bagged him two nominations for the Screen Actors Guild Awards.
DiCaprio, 32, has been nominated as a lead actor in the thriller Blood Diamond and in the supporting actor category for thriller The Departed.
Musical Dreamgirls, drama Babel and comedy Little Miss Sunshine were among those securing three nominations.
The ceremony is one of the main events in the run-up to next month's Oscars.
Dame Helen Mirren received a nomination for her lead role in The Queen.
Another Dame - Judi Dench - was also nominated for Notes on a Scandal, a film which also brought Cate Blanchett recognition in the supporting role category.
Other best actor nominees are Forest Whittaker for his role as Idi Amin in Last King of Scotland, Will Smith for In Pursuit of Happyness and veteran Peter O'Toole for Venus.
Penelope Cruz and Kate Winslet have also been nominated for best actress for playing housewives in Volver and Little Children, along with Meryl Streep's turn as the boss from hell in The Devil Wears Prada.
A second nomination for Blood Diamond is for Djimon Hounsou in the supporting actor category.
Other films in the running for the ensemble acting award alongside Dreamgirls, Babel and Little Miss Sunshine are The Departed and Bobby.
Babel also has supporting actress nominations for Adriana Barraza and Rinko Kikuchi. Little Miss Sunshine earned nominations for supporting actor Alan Arkin and supporting actress Abigail Breslin.
Dreamgirls grabbed supporting nominations for Eddie Murphy and Jennifer Hudson.
The Screen Actors Guild has 120,000 members drawn from the acting community in the US.
The awards - which this year are being held on 28 January - can be seen as a good indicator ahead of the Academy Awards, with three of last year's winners subsequently getting Oscars.