Aerosmith singer Steven Tyler will have throat surgery this week, forcing the rock giants to cancel the final 12 dates on their North American tour.
Tyler [L] and the group performed at the Grammy Awards in February
The band have been on the road since October and have already scrapped eight shows in the past two and a half weeks.
The group's spokeswoman said Tyler, 57, would be unable to sing for two or three months after the operation.
She said he was "doing fine" but declined to reveal further details of the singer's ailment.
"Despite Aerosmith's desire to keep the tour going as long as possible, Tyler's doctors advised him not to continue performing to give his voice time to recover," she said.
The band have no future plans for recording or touring, she added.
The tour was due to end in Sacramento, California, in mid-April.