Yoko Ono, Sinead O'Connor, Jeff Beck and Neil Finn are among the musicians who will appear at London's 2005 Meltdown festival in June.
Yoko Ono will appear at London's Queen Elizabeth Hall on 17 June
Punk singer Patti Smith has put the line-up together as artistic director of the two-week event, which is taking place at the South Bank Centre.
Also involved is Marc Almond in one of his first live performances since his motorcycle accident last October.
Previous Meltdown directors include Morrissey, David Bowie and Nick Cave.
In March, Smith said she wanted to "touch on all aspects of our culture" and "salute the best art there is, aesthetically and spiritually".
The events announced on Friday include tributes to playwright Bertolt Brecht, poet William Blake and guitarist Jimi Hendrix.
Almond was critically injured in a motorcycle accident in October
Almond will join Neil and Tim Finn in the Brecht event, entitled Stand Bravely Brothers, on 23 June.
O'Connor, meanwhile, will perform alongside singer-songwriters Beth Orton and Kristin Hersch in an evening of "protest songs and lullabies" to celebrate Blake's Songs of Innocence.
Beck and Smith will be joined by Flea and John Frusciante of the Red Hot Chili Peppers for an homage to Hendrix on 26 June.
And Smith will mark the 30th anniversary of her seminal album Horses by performing it in its entirety with Welsh composer John Cale, formerly of the Velvet Underground.
Left-wing singer Billy Bragg, country artist Steve Earle and recently reformed rock band Television are also scheduled to appear at the festival, which runs from 11 to 26 June.
Last year's Meltdown, directed by ex-Smiths singer Morrissey, included appearances by Jane Birkin, Nancy Sinatra and playwright Alan Bennett.