Redundancies are just part of the BBC's cost-cutting plans, director general Mark Thompson has told the Guardian.
Mr Thompson said he wanted to introduce a "new mindset"
"I don't think value for money is something you do and then stop doing," he is quoted as saying.
But he said he hoped the corporation would not have to repeat the "enormous correction" of the past year.
Last year Mr Thompson announced plans to shed 20% of the BBC's workforce during the next three years and reinvest the money saved in new shows.
His plans prompted a 24-hour strike by BBC staff who were members of the NUJ, Bectu and Amicus in May, although further action was averted following talks between the corporation and unions.
Mr Thompson said the BBC was facing up to its "biggest challenge" to date and that he wanted to introduce a "new mindset" among staff.
"In most industries productivity does not mean cutting quality," he said, adding he was hopeful most of the job cuts could be achieved through voluntary redundancies.
"We want to use as much of the licence fee as we can creating value rather than destroying value with bureaucracy and waste."
Jeremy Dear, general secretary of the National Union of Journalists, told the Guardian Mr Thompson's comments were not unexpected given upcoming negotiations with the government about the BBC licence fee.
However, he said unions would resume strike action if their concerns were not addressed.
"While he is warning us this may not be the end of the pain, we are also warning him that this isn't the end of his pain if we don't reach an agreement over compulsory redundancies."