Queen will headline a second Aids benefit concert in South Africa, which is being backed by former president Nelson Mandela.
More than 30,000 people turned out to watch last year's show
The 46664 South Africa show will raise awareness of the Nelson Mandela Foundation's continued fight against the disease.
The full line-up of international and South African artists will be unveiled early next year.
The first concert, in November 2003, starred Bono and Beyonce Knowles.
The 2005 concert will focus on the plight of women in sub-Saharan Africa, who are most affected by Aids.
Mr Mandela said: "46664 South Africa will build on the success of our truly memorable concert in Cape Town last year.
"It will serve to support the efforts of the Nelson Mandela Foundation and to show the world that South Africa is really addressing this most vital issue."
Last year's five-hour gig took place at the Greenpoint Stadium in Cape Town and featured appearances by the Eurythmics, Ms Dynamite, Peter Gabriel, The Corrs and Queen. It attracted more than 30,000 people.
Next year's event will take place at the Fancourt Hotel and Country Club Estate on 19 March.