Veteran TV presenter Sir David Frost is to end his long-running Sunday morning news programme and switch to presenting a new BBC interview series.
Sir David has interviewed the past six UK prime ministers
His agenda-setting Breakfast with Frost show will finish in about a year's time after 12 years on air.
World leaders such as Bill Clinton and Nelson Mandela have been among guests.
Sir David will continue to question people "at the heart of the news" in The Frost Interview, launched after the 2005 general election, the BBC said.
The new series is the result of a three-year deal between Sir David and the BBC.
During Sir David's 40-year career span he has interviewed many world figureheads, and is the only person to have questioned the last six UK prime ministers and the last seven US presidents.
Other famous faces from sport and showbusiness to have appeared include Sir Steve Redgrave, Sir Elton John and David Beckham.
Sir David said: "I'm enormously excited about the new series of interviews.
"The 12 years of Breakfast with Frost have been some of the most fulfilling years of my career but, once we're through the next election, I feel that the time will be right to ring the changes.
"The new series of interviews will allow us to bring additional insight to the key domestic and global issues and will, as ever, tackle the main players at the heart of the story."
Sir David appeared on satirical show That Was The Week That Was in the early 1960s.
But it was interviews with big name stars, including Muhammad Ali, Orson Welles and the Shah of Iran in the 1970s and 1980s, which made his name.
One of his most famous interviews was with former US President Richard Nixon in 1977 in which he tackled him about the Watergate affair.
Richard Sambrook, the BBC's outgoing director of news, said: "Sir David Frost has made and continues to make a huge contribution to the BBC's news and current affairs programming.
"His remarkable 40-year career has made him a household name and established him as one of the world's foremost interviewers."
Mr Sambrook said the new interviews "will capture the intellectual calibre and analysis of world events associated with Breakfast with Frost, reflecting the heart of the news agenda".