On Wednesday, President Barack Obama's government will announce new powers for the central bank of the US, the Federal Reserve, to oversee the relationships between financial institutions.
In future, the Fed will require interconnected firms to hold more capital in case of a crisis, to help avoid a repetition of events last year when the collapse of investment bank Lehman Brothers threatened to undermine the financial system.
Mr Darling told the BBC that the US regulatory changes would be catching up with the reforms made in the UK 10 years ago.
'Huge price'
Mr Darling will give more details of his plans in his annual Mansion House speech later on Wednesday.
"Having stabilised the banking sector, we are faced with the challenge of building a stronger, more efficient and more resilient financial sector in the future," he will say.
"Anyone who thinks that we can carry on as if nothing has happened should think again. In every country we are paying a huge price for this crisis. Not just the financial cost but also a profound social and human cost," he will add.
But the boardroom is where the focus should be, he will argue.
"I strongly believe that the process of learning lessons has to start in the boardroom. Bank boards must have the right people, skills and experience to manage themselves effectively their focus must be long-term wealth creation, not short-term profits."
Mr Darling also signalled a planned paper on reform of the banking industry will be much less forceful than the Treasury had originally suggested.
The paper, which is expected to be published in about a fortnight, will be a consultative green paper, rather than a policy-setting white paper.
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