German pharmaceutical firm Bayer's 2.3bn euro (£1.6bn) purchase of Roche's over-the-counter drugs unit has been cleared by the European Commission.
The deal brings together many famous medicines
The deal will transform Bayer into the world's third-largest supplier of over-the-counter medicines behind Johnson & Johnson and GlaxoSmithKline.
The deal will bring together famous brands such as Alka-Seltzer and Rennie.
To satisfy competition issues, Bayer will have to sell off a number of drugs and trademarks in Austria and Ireland.
The combined business, whose headquarters will be in the United States, will employ 6,700 staff worldwide.
"The clearance is subject to a number of conditions intended to safeguard competition and hence the interests of European consumers," the Commission said in a statement.
The deal is expected to be completed before the end of the year.