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Police spokesman, Dola Indidis, told reporters that seven children were among those killed when the two buses collided at Kapkantugor near Kericho.
He said 58 more people who sustained various injuries, are now being treating in hospitals in the area.
The two buses - one belonging to the Akamba company and the other operated by Shaggy - were travelling in opposite directions when they collided.
The Akamba bus was travelling from the lakeside town of Kisumu and the other was going to Kakamega .
Cause of collision
Both buses overturned on impact, and the Akamba bus exploded into flames.
 Estimates say 2,000 people die in road accidents every year in Kenya
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But Mr Indidis said one of the buses had lost control in a sharp corner and run into the other's path.
Road accidents are a serious problem in Kenya, with some estimates saying that about 2,000 people are killed every year on the country's roads.
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