The UN Security Council has unanimously passed a resolution condemning militias and other armed groups destabilising central Africa's Great Lakes region.
The 1994 Rwandan genocide still casts a shadow over the region
The vote followed a marathon debate in which foreign ministers from more than 10 countries in the area took part.
The vote came just days after eight UN peacekeepers were killed in the Democratic Republic of Congo by Uganda's rebel Lord's Resistance Army.
Conflicts in the Great Lakes have led to millions of deaths.
In Rwanda alone, some 800,000 people were killed in the 1994 genocide.
The Security Council debate heard also from diplomats and special envoys to the region.
The murders of the UN peacekeepers from Guatemala by the Lord's Resistance Army (LRA) were condemned by several African foreign ministers.
DR Congo's Foreign Minister Raymond Bayaramazani said the incident strengthened his government's determination to eradicate all armed groups along the eastern border.
The LRA has become notorious for its atrocities against civilians in northern Uganda and its abduction of children.
Ugandan Foreign Minister Sam Kutesa said there was "an historic opportunity" for the international community "to decisively deal" with the LRA.
However, the BBC's Susannah Price at the UN says there were some positive notes, with speakers praising the continuing electoral process in the Democratic Republic of Congo and the progress made by Burundi as it emerges from years of civil war.
Belgian Foreign Minister Karel de Gucht said the Great Lakes region had the potential to become the motor of African development.