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A chronology of key events:
4th century
- Bantu speaking groups settle, joining the indigenous San and Khoikhoi people.
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Nelson Mandela: Ex-prisoner and revered statesman
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1480s
- Portuguese navigator Bartholomeu Dias is the first European to travel round the southern tip of Africa.
1497
- Portuguese explorer Vasco da Gama lands on Natal coast.
1652
- Jan van Riebeeck, representing the Dutch East India Company, founds the Cape Colony at Table Bay.
1795
- British forces seize Cape Colony from the Netherlands. Territory is returned to the Dutch in 1803; ceded to the British in 1806.
1816-1826
- Shaka Zulu founds and expands the Zulu empire, creates a formidable fighting force.
1835-1840
- Boers leave Cape Colony in the 'Great Trek' and found the Orange Free State and the Transvaal.
1852
- British grant limited self-government to the Transvaal.
1856
- Natal separates from the Cape Colony.
Late 1850s
- Boers proclaim the Transvaal a republic.
1867
- Diamonds discovered at Kimberley.
1877
- Britain annexes the Transvaal.
1879
- British defeat the Zulus in Natal.
1880-81
- Boers rebel against the British, sparking the first Anglo-Boer War. Conflict ends with a negotiated peace. Transvaal is restored as a republic.
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Elephants roam South African parks in their thousands
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Mid 1880s
- Gold is discovered in the Transvaal, triggering the gold rush.
1899
- British troops gather on the Transvaal border and ignore an ultimatum to disperse. The second Anglo-Boer War begins.
1902
- Treaty of Vereeniging ends the second Anglo-Boer War. The Transvaal and Orange Free State are made self-governing colonies of the British Empire.
1910
- Formation of Union of South Africa by former British colonies of the Cape and Natal, and the Boer republics of Transvaal, and Orange Free State.
1912
- Native National Congress founded, later renamed the African National Congress (ANC).
1913
- Land Act introduced to prevent blacks, except those living in Cape Province, from buying land outside reserves.
1914
- National Party founded.
1918
- Secret Broederbond (brotherhood) established to advance the Afrikaner cause.
1919
- South West Africa (Namibia) comes under South African administration.
Apartheid set in law
1948
- Policy of apartheid (separateness) adopted when National Party (NP) takes power.
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Soweto, 1976: Black anger boiled over; hundreds died in clashes
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1950
- Population classified by race. Group Areas Act passed to segregate blacks and whites. Communist Party banned. ANC responds with campaign of civil disobedience, led by Nelson Mandela.
1960
- Seventy black demonstrators killed at Sharpeville. ANC banned.
1961
- South Africa declared a republic, leaves the Commonwealth. Mandela heads ANC's new military wing, which launches sabotage campaign.
1960s
- International pressure against government begins, South Africa excluded from Olympic Games.
1964
- ANC leader Nelson Mandela sentenced to life imprisonment.
1966
September - Prime Minister Hendrik Verwoerd assassinated.
1970s
- More than 3 million people forcibly resettled in black 'homelands'.
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Black Consciousness Movement leader Steve Biko died in custody
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1976
- More than 600 killed in clashes between black protesters and security forces during uprising which starts in Soweto.
1984-89
- Township revolt, state of emergency.
1989
- FW de Klerk replaces PW Botha as president, meets Mandela. Public facilities desegregated. Many ANC activists freed.
1990
- ANC unbanned, Mandela released after 27 years in prison. Namibia becomes independent.
1991
- Start of multi-party talks. De Klerk repeals remaining apartheid laws, international sanctions lifted. Major fighting between ANC and Zulu Inkatha movement.
1993
- Agreement on interim constitution.
1994
April - ANC wins first non-racial elections. Mandela become president, Government of National Unity formed, Commonwealth membership restored, remaining sanctions lifted. South Africa takes seat in UN General Assembly after 20-year absence.
Seeking truth
1996
- Truth and Reconciliation Commission chaired by Archbishop Desmond Tutu begins hearings on human rights crimes committed by former government and liberation movements during apartheid era.
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FW DE KLERK
Oversaw end of apartheid; won Nobel Peace Prize with Mandela
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1996
- Parliament adopts new constitution. National Party withdraws from coalition, saying it is being ignored.
1998
- Truth and Reconciliation Commission report brands apartheid a crime against humanity and finds the ANC accountable for human rights abuses.
1999
- ANC wins general elections, Thabo Mbeki takes over as president.
2000
December - ANC prevails in local elections. Recently-formed Democratic Alliance captures nearly a quarter of the votes. The Inkatha Freedom Party wins 9%.
2001
April - 39 multi-national pharmaceutical companies halt a legal battle to stop South Africa importing generic Aids drugs. The decision is hailed as a victory for the world's poorest countries in their efforts to import cheaper drugs to combat the virus.
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Aids activists pressed for anti-retroviral drugs
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2001
May - An official panel considers allegations of corruption surrounding a 1999 arms deal involving British, French, German, Italian, Swedish and South African firms. In November the panel clears the government of unlawful conduct.
2001
September - Durban hosts UN race conference.
2001
December - High Court rules that pregnant women must be given Aids drugs to help prevent transmission of the virus to their babies.
2002
April - Court acquits Dr Wouter Basson - dubbed "Dr Death" - who ran apartheid-era germ warfare programme. Basson had faced charges of murder and conspiracy. ANC condemns verdict.
2002
July - Constitutional court orders government to provide key anti-Aids drug at all public hospitals. Government had argued drug was too costly.
2002
October - Bomb explosions in Soweto and a blast near Pretoria are thought to be the work of right-wing extremists. Separately, police charge 17 right-wingers with plotting against the state.
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Walter Sisulu: Mandela's mentor spent 26 years in prison
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2003
May - Walter Sisulu, a key figure in the anti-apartheid struggle, dies aged 91. Thousands gather to pay their last respects.
2003
November - Government approves major programme to treat and tackle HIV/Aids. It envisages network of drug-distributon centres and preventative programmes. Cabinet had previously refused to provide anti-Aids medicine via public health system.
2004
April - Ruling ANC wins landslide election victory, gaining nearly 70% of votes. Thabo Mbeki begins a second term as president. Inkatha Freedom Party leader Mangosuthu Buthelezi is dropped from the cabinet.
2005
March - Investigators exhume the first bodies in a Truth and Reconciliation Commission investigation into the fates of hundreds of people who disappeared in the apartheid era.
2005
May - Geographical names committee recommends that the culture minister should approve a name change for the capital from Pretoria to Tshwane.
Zuma sacked
2005
June - President Mbeki sacks his deputy, Jacob Zuma, in the aftermath of a corruption case.
2005
August - Around 100,000 gold miners strike over pay, bringing the industry to a standstill.
2006
May - Former deputy president Jacob Zuma is acquitted of rape charges by the High Court in Johannesburg. He is reinstated as deputy leader of the governing African National Congress.
2006
June - Chinese Premier Wen Jiabao visits and promises to limit clothing exports to help South Africa's ailing textile industry.
2006
September - Corruption charges against former deputy president Zuma are dismissed, boosting his bid for the presidency.
2006
December - South Africa becomes the first African country, and the fifth in the world, to allow same-sex unions.
2007
April - President Mbeki, often accused of turning a blind eye to crime, urges South Africans to join forces to bring rapists, drug dealers and corrupt officials to justice.
2007
May - Cape Town mayor Helen Zille is elected as new leader of the main opposition Democratic Alliance (DA).
Mass strike
2007
June - Hundreds of thousands of public-sector workers take part in the biggest strike since the end of apartheid. The strike lasts for four weeks and causes widespread disruption to schools, hospitals and public transport.
2007
December - Zuma is elected chairman of the ANC, placing him in a strong position to become the next president. Prosecutors bring new corruption charges against him.
2008
May - Wave of violence directed at foreigners hits townships across the country. Dozens of people die and thousands of Zimbabweans, Malawians and Mozambicans return home.
2008
September - A judge throws out a corruption case against ruling ANC party chief Jacob Zuma, opening the way for him to stand as the country's president in 2009.
President Mbeki resigns over allegations that he interfered in the corruption case against Mr Zuma. ANC deputy leader Kgalema Motlanthe is chosen by parliament as president.
New party launched
2008
December - A new political party is launched in Bloemfontein, in the first real challenge to the governing ANC. The Congress of the People - or Cope - is made up largely of defectors from the ANC and is headed by former defence minister Mosiuoa Lekota.
2009
January - Appeals court rules that state prosecutors can resurrect their corruption case against ANC leader Jacob Zuma, opening the way for Mr Zuma's trial to be resumed, just months before general election.
2009
February - South Africa's new Cope party chooses Methodist bishop Mvume Dandala as its presidential candidate.
2009
April - Public prosecutors drop corruption case against Jacob Zuma. ANC wins general election.
2009
May - Parliament elects Jacob Zuma as president.
President Zuma appoints cabinet with some significant changes - veteran finance minister Trevor Manuel is replaced by Pravin Gordhan, Aaron Motsoaledi takes over as health minister to tackle the HIV/Aids epidemic, outgoing president Kgalema Motlanthe becomes deputy president and Dr Pieter Mulder of the Afrikaner nationalist Freedom Front Plus party is appointed deputy agriculture minister.
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