An air ambulance was called to the incident
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The centre of Llanelli was closed off on Thursday afternoon after a man fell off the roof of one of the town's biggest buildings.
An air ambulance was called following the incident at the Tinopolis television production studios in Park Street.
The man, who is around 30 and believed to be local, was then flown to Morriston Hospital in Swansea.
Dyfed-Powys Police say he fell around 30 feet from the multi-storey car park which forms part of the building.
He is described as having serious head injuries.
The incident, which happened around 1345 BST, is not believed to be suspicious.