Arsen Wenger looks forward to Arsenal's crunch match in Kiev

The Highbury boss already knew striker Dennis Bergkamp would be unavailable for the trip to Ukraine because of his fear of air travel - and hopes of captain Adams recovering from back trouble despite missing the last two games have now also disappeared.

But the loss of Overmars is a stunning extra setback.

Bergkamp's fellow Dutchman has an abdominal injury which forced his substitution late in the game against Coventry on Saturday and he will not even make the journey to Kiev.

Wenger was set to switch him from the wing to take Bergkamp's place alongside Nicolas Anelka in attack.

Now the job will almost certainly go to Liberian international Christopher Wreh, who has recovered from the ankle injury which kept him out of the Coventry game.

Steve Bould, 36 in two weeks, will stay in as Adams' replacement in central defence and also retain the captaincy.

Now Wenger must decide between Portuguese winger Luis Boa Morte and former England Under-21 midfielder Stephen Hughes for a role on the left.

He said: "I have the plan of the team in my mind already, but it is just one or two positions I'm not sure about yet tactically.

"Of course it is a big problem losing so many top players especially for a game like this, but I have faith in my squad.

"We have produced results many times when important players have been missing."

Arsenal go to the Ukraine following a 1-1 draw with Kiev at Wembley two weeks ago. Only a last-minute equaliser by Sergei Rebrov stopped them winning, but the Gunners were outplayed for long spells in the match before Bergkamp's goal put them in front.

Dynamo, whom Wenger named as the favourites to win Group E and progress automatically to the quarter-finals have still to score their first victory but will climb over Arsenal on goal difference if they beat them in the 100,000 capacity Olympic Stadium on Wednesday night.

Andrei Shevchenko, their talented centre-forward whom AC Milan want to buy for £18million, injured an ankle in the game against CSKA Kiev last week, but Wenger said: "I expect him to play against us. Russian doctors can make miracles."