Europe South Asia Asia Pacific Americas Middle East Africa BBC Homepage World Service Education



Front Page

World

UK

UK Politics

Business

Sci/Tech

Health

Education

Sport

Entertainment

Talking Point
On Air
Feedback
Low Graphics
Help

Wednesday, October 28, 1998 Published at 01:36 GMT


Health

Cancer cells give hope to stroke victims

Surgery is carried out under local anaesthetic

Scientists are injecting modified cells from testicular tumours into the brains of stroke victims to help them regain movement following paralysis.

Don Fitch, from Pittsburgh, is one of the first 12 people in the world to undergo the new treatment. His progress is featured in the BBC One television programme Tomorrow's World on Wednesday.

Don hopes to regain the use of his left arm three years after a stroke left his left side partially paralysed.

A small area of Don's brain was damaged when a clot lodged itself in his brain.

Until now, scientists have been unable to reverse the effects of brain damage as brain cells, known as neurones, could not be repaired once they were damaged.


[ image: Don Fitch: Lost use of his arm]
Don Fitch: Lost use of his arm
But Don plans to take advantage of a new technique that has given stroke victims hope of at least a partial recovery.

He is to have millions of manufactured human nerve cells - made from cells taken from testicles - implanted into his brain.

Scientists believe the new cells will link up with existing brain cells to repair the damage caused by the stroke.

Neurosurgeon Douglas Kondziolka, who leads the surgical team, said: "We are going to put the cells not just into the stroke area, but beyond it and hope that the cells will then graft, link up with the existing brain cells that are still livings and create a better regional environment - an environment that perhaps wants to move the arm."


[ image: Douglas Kondziolka: Developed the technique]
Douglas Kondziolka: Developed the technique
The operation has become possible because scientists stumbled upon a new way of growing nerve cells in the laboratory.

They discovered that they can take immature cells from a testicular tumour, stimulate them to replicate many times and then treat them with a body chemical to turn them into nerve cells suitable to transplant into the brain.

Dr Kondziolka said: "These cells will hopefully help the local environment to release different types of growth factors, neurotransmitters, and help the brain talk to itself better and translate into better function."

The operation itself is relatively quick and is carried out under local anaesthetic.

A single hole is drilled through the skull, and a tube is inserted into the brain to deliver the cells.

If the brain cell transplants prove to be safe and effective the procedure could be used for many forms of brain damage, from Parkinson's Disease to head injuries.

Don will have to wait for six months to find out if the surgery is a success.

"It's all over bar the shouting, and when my arm starts moving I am going to start shouting," he said.

Tomorrow's World is broadcast on BBC One at 1930 GMT on Wednesday 28 October.



Advanced options | Search tips




Back to top | BBC News Home | BBC Homepage | ©


Health Contents

Background Briefings
Medical notes

Relevant Stories

21 Oct 98 | Health
Neutron beams used to treat brain cancer

20 Oct 98 | Health
Brain injury victims cannot find work

08 Sep 98 | Health
Brain tumour surgery without the scalpel

23 Aug 98 | Health
Brain implants may control Alzheimer's Disease





Internet Links


The Stroke Association

Neurological websites

Brain chemistry


The BBC is not responsible for the content of external internet sites.




In this section

Disability in depth

Spotlight: Bristol inquiry

Antibiotics: A fading wonder

Mental health: An overview

Alternative medicine: A growth industry

The meningitis files

Long-term care: A special report

Aids up close

From cradle to grave

NHS reforms: A guide

NHS Performance 1999

From Special Report
NHS in crisis: Special report

British Medical Association conference '99

Royal College of Nursing conference '99