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Sunday, October 25, 1998 Published at 12:50 GMT Sci/Tech Glow-in-the-dark genes ![]() Genes are extracted from animals that make their own light By Brian Barron in Pittsburgh
To raise money for their research, the Pittsburgh-based scientists have turned some of the luminous genes into novelty products.
"Eighty per cent of animals that live below hundred meters in the ocean make their own light. So we harvest these creatures from under the ocean and then we extract the genes by cloning," says Dr Gene Finley, President of the Prolume. Making tumours glow Prolume and its rivals have created genetic libraries for 25 sea creatures. Then the genes are spliced into protein-making bacteria which multiply by the billions.
"If we're successful, a surgeon will be able to inject a patient with, in effect, a dye that will be based on bioluminescents. And then, as he operates on the patient, be able to see the tumour as a visible glowing item," says Dr Byron Ballou, the Vice president of Prolume in charge of research and development. He says this could be a life saving technology. "It could also make surgery a lot quicker and easier. That's what we're hoping for," he says. Squirt gun fundraising It could take from five to ten years to perfect such products for everyday medical use.
There is also a line in glowing drinks. "How would you like to open a bottle of champagne - and have it glow?" Dr Byron asks. "We've even demonstrated this stuff to the CIA because they're interested in document validation. They want to have secret messages that they can send to their spies," Dr Finley says.
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