The Leicester venue is a backdrop to the comedy out in 2006
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Martin Kemp, Dennis Waterman and Chris Barrie are starring in a film partly shot at the National Space Centre.
The comedy Back in Business, released next year, was partly rewritten to use the Leicester venue as a backdrop to the tale about confidence tricksters.
The conmen pair up for a final heist involving a moon buggy before they head off to retire in Marbella.
Other locations include the Houses of Parliament and Windsor Castle. The film is directed by Chris Munro.
Dressing gown
Filming takes place in Leicester on Mondays when the centre is closed to the public.
The New Light Films production also stars Stefan Booth, of William and Mary, and Hollyoaks' Joanna Taylor.
Malika Andress, from the Space Centre, said: "Going downstairs at work you normally see children running around and people looking at space exhibits, but there was a woman in very high stilettos, very blonde hair and a dressing gown walking round in the gallery.
"It was very different."